1.4M XNYS Volume
XNYS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 122.02 per share. | 17 Mar 2025 | 1,907 | 21,785 (0%) | 0% | 122.0 | 232,691 | Common Stock |
| Dow R. Wilson | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 18,066 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 20,493 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 9,929 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 812 | 10,741 (0%) | 0% | 121.2 | 98,398 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 37,555 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Boon Hwee Koh | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 62,114 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Boon Hwee Koh | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 121.18 per share. | 14 Mar 2025 | 546 | 61,568 (0%) | 0% | 121.2 | 66,164 | Common Stock |
| Heidi Kunz | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 58,851 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| G. Mikael Dolsten | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 7,549 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Susan H. Rataj | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 21,459 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Mala Anand | Director | Grant, award, or other acquisition of securities at price $ 121.18 per share. | 14 Mar 2025 | 1,819 | 14,547 (0%) | 0% | 121.2 | 220,426 | Common Stock |
| Susan H. Rataj | Director | Sale of securities on an exchange or to another person at price $ 126.38 per share. | 06 Mar 2025 | 6,971 | 19,640 (0%) | 0% | 126.4 | 881,009 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 126.51 per share. | 05 Mar 2025 | 5,385 | 172,191 (0%) | 0% | 126.5 | 681,256 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.92 per share. | 28 Feb 2025 | 278 | 39,374 (0%) | 0% | 127.9 | 35,562 | Common Stock |
| Angelica Riemann | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.92 per share. | 28 Feb 2025 | 84 | 18,992 (0%) | 0% | 127.9 | 10,745 | Common Stock |
| Jonah Prevost Kirkwood | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.92 per share. | 28 Feb 2025 | 124 | 8,189 (0%) | 0% | 127.9 | 15,862 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 150.36 per share. | 28 Jan 2025 | 7,148 | 16,544 (0%) | 0% | 150.4 | 1,074,778 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 150.36 per share. | 28 Jan 2025 | 7,148 | 7,189 (0%) | 0% | 150.4 | 1,074,778 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 150.36 per share. | 28 Jan 2025 | 7,148 | 23,693 (0%) | 0% | 150.4 | 1,074,778 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 150.36 per share. | 28 Jan 2025 | 7,148 | 40 (0%) | 0% | 150.4 | 1,074,778 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 21 Jan 2025 | 1,911 | 39,652 (0%) | 0% | 150 | 286,650 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 137.97 per share. | 29 Nov 2024 | 2,577 | 88,097 (0%) | 0% | 138.0 | 355,549 | Common Stock |
| Henrik Ancher-Jensen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 4,336 | 90,674 (0%) | 0% | 138.1 | 598,975 | Common Stock |
| Henrik Ancher-Jensen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 12,517 | 12,517 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 6,423 | 166,762 (0%) | 0% | 138.1 | 887,273 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 18,544 | 18,544 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 3,941 | 3,941 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 1,365 | 23,671 (0%) | 0% | 138.1 | 188,561 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 15,656 | 41,563 (0%) | 0% | 138.1 | 2,162,720 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 45,202 | 45,202 | - | - | Employee Stock Option (Right to Buy) | |
| Angelica Riemann | Senior Vice President | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 3,212 | 19,054 (0%) | 0% | 138.1 | 443,706 | Common Stock |
| Angelica Riemann | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 9,272 | 9,272 | - | - | Employee Stock Option (Right to Buy) | |
| Jonah Prevost Kirkwood | Senior Vice President | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 3,212 | 8,313 (0%) | 0% | 138.1 | 443,706 | Common Stock |
| Jonah Prevost Kirkwood | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 9,272 | 9,272 | - | - | Employee Stock Option (Right to Buy) | |
| Jianmiao Mike Zhang | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Nov 2024 | 7,418 | 7,418 | - | - | Employee Stock Option (Right to Buy) | |
| Jianmiao Mike Zhang | Senior Vice President | Grant, award, or other acquisition of securities at price $ 138.14 per share. | 27 Nov 2024 | 2,569 | 5,796 (0%) | 0% | 138.1 | 354,882 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.84 per share. | 22 Nov 2024 | 581 | 86,338 (0%) | 0% | 133.8 | 77,761 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.84 per share. | 22 Nov 2024 | 5,775 | 160,339 (0%) | 0% | 133.8 | 772,926 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.84 per share. | 22 Nov 2024 | 138 | 22,306 (0%) | 0% | 133.8 | 18,470 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.84 per share. | 22 Nov 2024 | 448 | 25,907 (0%) | 0% | 133.8 | 59,960 | Common Stock |
| Angelica Riemann | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.83 per share. | 22 Nov 2024 | 54 | 15,842 (0%) | 0% | 133.8 | 7,227 | Common Stock |
| Jonah Prevost Kirkwood | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.84 per share. | 22 Nov 2024 | 113 | 5,101 (0%) | 0% | 133.8 | 15,124 | Common Stock |
| Jianmiao Mike Zhang | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 133.85 per share. | 22 Nov 2024 | 65 | 3,227 (0%) | 0% | 133.8 | 8,700 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 7,954 | 89,910 (0%) | 0% | 125.7 | 999,738 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 125.69 per share. | 19 Nov 2024 | 2,991 | 86,919 (0%) | 0% | 125.7 | 375,939 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 125.69 per share. | 19 Nov 2024 | 2,196 | 166,114 (0%) | 0% | 125.7 | 276,015 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 7,835 | 168,310 (0%) | 0% | 125.7 | 984,781 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 125.69 per share. | 19 Nov 2024 | 591 | 22,444 (0%) | 0% | 125.7 | 74,283 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 1,698 | 23,035 (0%) | 0% | 125.7 | 213,422 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 4,505 | 27,861 (0%) | 0% | 125.7 | 566,233 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 125.69 per share. | 19 Nov 2024 | 1,506 | 26,355 (0%) | 0% | 125.7 | 189,289 | Common Stock |
| Angelica Riemann | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 125.69 per share. | 19 Nov 2024 | 327 | 15,896 (0%) | 0% | 125.7 | 41,101 | Common Stock |
| Angelica Riemann | Senior Vice President | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 1,045 | 16,223 (0%) | 0% | 125.7 | 131,346 | Common Stock |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 125.69 per share. | 19 Nov 2024 | 653 | 10,650 (0%) | 0% | 125.7 | 82,076 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.07 per share. | 15 Nov 2024 | 796 | 81,956 (0%) | 0% | 127.1 | 101,148 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.07 per share. | 15 Nov 2024 | 1,295 | 160,475 (0%) | 0% | 127.1 | 164,556 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.07 per share. | 15 Nov 2024 | 276 | 21,337 (0%) | 0% | 127.1 | 35,071 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.07 per share. | 15 Nov 2024 | 715 | 23,356 (0%) | 0% | 127.1 | 90,855 | Common Stock |
| Angelica Riemann | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.07 per share. | 15 Nov 2024 | 172 | 15,178 (0%) | 0% | 127.1 | 21,856 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 27 Sep 2024 | 47 | 24,071 (0%) | 0% | 150 | 7,050 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 145.00 per share. | 26 Sep 2024 | 5,010 | 46,761 (0%) | 0% | 145 | 726,450 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 145.00 per share. | 26 Sep 2024 | 9,990 | 40,010 (0%) | 0% | 145 | 1,448,550 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 145.00 per share. | 22 Aug 2024 | 1,958 | 24,118 (0%) | 0% | 145 | 283,910 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 140.00 per share. | 26 Jul 2024 | 1,958 | 26,076 (0%) | 0% | 140 | 274,120 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 135.00 per share. | 18 Jun 2024 | 1,958 | 28,034 (0%) | 0% | 135 | 264,330 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 133.28 per share. | 10 Jun 2024 | 15,000 | 49,485 (0%) | 0% | 133.3 | 1,999,262 | Common Stock |
| Dominique Grau | Senior Vice President | Gift of securities by or to the insider at price $ 133.56 per share. | 05 Jun 2024 | 515 | 52,801 (0%) | 0% | 133.6 | 68,783 | Common Stock |
| Dominique Grau | Senior Vice President | Gift of securities by or to the insider at price $ 133.56 per share. | 05 Jun 2024 | 515 | 64,485 (0%) | 0% | 133.6 | 68,783 | Common Stock |
| Dominique Grau | Senior Vice President | Gift of securities by or to the insider at price $ 133.56 per share. | 05 Jun 2024 | 515 | 51,771 (0%) | 0% | 133.6 | 68,783 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 131.40 per share. | 03 Jun 2024 | 4,807 | 29,992 (0%) | 0% | 131.4 | 631,640 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 130.00 per share. | 03 Jun 2024 | 1,958 | 25,185 (0%) | 0% | 130 | 254,540 | Common Stock |
| George A. Scangos | Director | Gift of securities by or to the insider at price $ 145.48 per share. | 29 May 2024 | 3,443 | 18,577 (0%) | 0% | 145.5 | 500,888 | Common Stock |
| George A. Scangos | Director | Gift of securities by or to the insider at price $ 145.48 per share. | 29 May 2024 | 3,443 | 17,893 (0%) | 0% | 145.5 | 500,888 | Common Stock |
| Padraig McDonnell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.23 per share. | 17 May 2024 | 174 | 27,143 (0%) | 0% | 154.2 | 26,836 | Common Stock |
| Angelica Riemann | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.23 per share. | 17 May 2024 | 26 | 15,254 (0%) | 0% | 154.2 | 4,010 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 139.45 per share. | 03 May 2024 | 132 | 82,559 (0%) | 0% | 139.4 | 18,407 | Common Stock |
| Philip Binns | Senior Vice President | Sale of securities on an exchange or to another person at price $ 147.54 per share. | 25 Mar 2024 | 2,827 | 9,997 (0%) | 0% | 147.5 | 417,096 | Common Stock |
| Dow R. Wilson | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 16,136 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 21,989 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 7,305 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 750 | 8,055 (0%) | 0% | 147.5 | 110,610 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 35,082 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 410 | 35,492 (0%) | 0% | 147.5 | 60,467 | Common Stock |
| Boon Hwee Koh | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.48 per share. | 15 Mar 2024 | 504 | 60,204 (0%) | 0% | 147.5 | 74,330 | Common Stock |
| Boon Hwee Koh | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 60,708 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 750 | 24,976 (0%) | 0% | 147.5 | 110,610 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 24,226 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Heidi Kunz | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 56,653 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Mikael Dolsten | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 5,711 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Susan H. Rataj | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 26,611 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Mala Anand | Director | Grant, award, or other acquisition of securities at price $ 147.48 per share. | 15 Mar 2024 | 1,678 | 12,728 (0%) | 0% | 147.5 | 247,471 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 08 Mar 2024 | 52,297 | 253,908 (0%) | 0% | 150 | 7,844,550 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 149.00 per share. | 07 Mar 2024 | 4,828 | 21,329 (0%) | 0% | 149.0 | 719,348 | Common Stock |
| Heidi Kunz | Director | Sale of securities on an exchange or to another person at price $ 144.34 per share. | 05 Mar 2024 | 1,658 | 54,975 (0%) | 0% | 144.3 | 239,316 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 139.06 per share. | 01 Mar 2024 | 3,202 | 27,317 (0%) | 0% | 139.1 | 445,270 | Common Stock |
| Angelica Riemann | Senior Vice President | Grant, award, or other acquisition of securities at price $ 139.06 per share. | 01 Mar 2024 | 880 | 15,084 (0%) | 0% | 139.1 | 122,373 | Common Stock |
| Philip Binns | Senior Vice President | Sale of securities on an exchange or to another person at price $ 139.78 per share. | 27 Dec 2023 | 2,880 | 12,824 (0%) | 0% | 139.8 | 402,566 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 137.69 per share. | 18 Dec 2023 | 1,500 | 26,132 (0%) | 0% | 137.7 | 206,538 | Common Stock |
| Ancher-Jensen Henrik | Sr Vice President | Sale of securities on an exchange or to another person at price $ 138.36 per share. | 15 Dec 2023 | 26,331 | 82,503 (0%) | 0% | 138.4 | 3,643,157 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2023 | 1,399 | 4,199 | - | - | Employee Stock Option (Right to Buy) | |
| Ancher-Jensen Henrik | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2023 | 10,304 | 3,435 | - | - | Employee Stock Option (Right-to-Buy) | |
| Ancher-Jensen Henrik | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 122.40 per share. | 15 Dec 2023 | 1,399 | 108,834 (0%) | 0% | 122.4 | 171,238 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 109.86 per share. | 15 Dec 2023 | 10,304 | 107,435 (0%) | 0% | 109.9 | 1,131,997 | Common Stock |
| McMullen R. Michael | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2023 | 2,751 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.12 per share. | 13 Dec 2023 | 2,751 | 308,956 (0%) | 0% | 42.1 | 115,872 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.00 per share. | 13 Dec 2023 | 2,751 | 306,205 (0%) | 0% | 130 | 357,630 | Common Stock |
| McMullen Michael R. | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.12 per share. | 07 Dec 2023 | 62,467 | 368,672 (0%) | 0% | 42.1 | 2,631,110 | Common Stock |
| McMullen R. Michael | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Dec 2023 | 62,467 | 2,751 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.00 per share. | 07 Dec 2023 | 62,467 | 306,205 (0%) | 0% | 130 | 8,120,710 | Common Stock |
| Grau Dominique | Senior Vice President | Grant, award, or other acquisition of securities at price $ 128.79 per share. | 01 Dec 2023 | 16,614 | 64,861 (0%) | 0% | 128.8 | 2,139,717 | Common Stock |
| Ancher-Jensen Henrik | Sr Vice President | Grant, award, or other acquisition of securities at price $ 128.79 per share. | 01 Dec 2023 | 16,614 | 97,131 (0%) | 0% | 128.8 | 2,139,717 | Common Stock |
| R. McMullen Michael | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 71,449 | 71,449 | - | - | Employee Stock Option (Right to Buy) | |
| McMullen Michael R. | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 25,195 | 306,205 (0%) | 0% | 124.0 | 3,123,928 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 4,940 | 80,517 (0%) | 0% | 124.0 | 612,511 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 14,010 | 14,010 | - | - | Employee Stock Option (Right to Buy) | |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 4,150 | 54,872 (0%) | 0% | 124.0 | 514,559 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 11,768 | 11,768 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 7,312 | 132,350 (0%) | 0% | 124.0 | 906,615 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 20,734 | 20,734 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 29,641 | 161,991 (0%) | 0% | 124.0 | 3,675,188 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 4,051 | 48,247 (0%) | 0% | 124.0 | 502,283 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 11,488 | 11,488 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 4,483 | 4,483 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 1,581 | 27,632 (0%) | 0% | 124.0 | 196,028 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 4,347 | 24,115 (0%) | 0% | 124.0 | 538,985 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 12,328 | 12,328 | - | - | Employee Stock Option (Right to Buy) | |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 123.99 per share. | 22 Nov 2023 | 3,557 | 15,704 (0%) | 0% | 124.0 | 441,032 | Common Stock |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Nov 2023 | 10,087 | 10,087 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 10,206 | 281,010 (0%) | 0% | 113.2 | 1,154,809 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 1,382 | 75,577 (0%) | 0% | 113.1 | 156,373 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 1,446 | 50,722 (0%) | 0% | 113.2 | 163,615 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 2,429 | 125,038 (0%) | 0% | 113.1 | 274,841 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 1,587 | 44,196 (0%) | 0% | 113.1 | 179,569 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 356 | 26,051 (0%) | 0% | 113.1 | 40,281 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 1,578 | 85,107 (0%) | 0% | 113.2 | 178,551 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.15 per share. | 17 Nov 2023 | 587 | 19,768 (0%) | 0% | 113.1 | 66,419 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 2,013 | 291,216 (0%) | 0% | 114.2 | 229,864 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 375 | 76,959 (0%) | 0% | 114.2 | 42,821 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 286 | 52,168 (0%) | 0% | 114.2 | 32,658 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 504 | 127,467 (0%) | 0% | 114.2 | 57,552 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 349 | 45,783 (0%) | 0% | 114.2 | 39,852 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 77 | 26,407 (0%) | 0% | 114.2 | 8,793 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 345 | 86,685 (0%) | 0% | 114.2 | 39,396 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 114.19 per share. | 16 Nov 2023 | 290 | 20,355 (0%) | 0% | 114.2 | 33,115 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 2,510 | 293,229 (0%) | 0% | 113.6 | 285,136 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 406 | 77,334 (0%) | 0% | 113.6 | 46,122 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 359 | 52,454 (0%) | 0% | 113.6 | 40,782 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 369 | 46,132 (0%) | 0% | 113.6 | 41,918 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 98 | 26,484 (0%) | 0% | 113.6 | 11,133 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.60 per share. | 15 Nov 2023 | 394 | 20,645 (0%) | 0% | 113.6 | 44,758 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 66,748 | 327,616 (0%) | 0% | 111.6 | 7,449,744 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 31,877 | 295,739 (0%) | 0% | 111.6 | 3,557,792 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 10,012 | 81,177 (0%) | 0% | 111.6 | 1,117,439 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 3,437 | 77,740 (0%) | 0% | 111.6 | 383,604 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 3,471 | 52,813 (0%) | 0% | 111.6 | 387,398 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 9,709 | 56,284 (0%) | 0% | 111.6 | 1,083,621 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 16,687 | 132,883 (0%) | 0% | 111.6 | 1,862,436 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 4,640 | 128,243 (0%) | 0% | 111.6 | 517,870 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 3,478 | 46,501 (0%) | 0% | 111.6 | 388,180 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 9,709 | 49,979 (0%) | 0% | 111.6 | 1,083,621 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 3,490 | 27,790 (0%) | 0% | 111.6 | 389,519 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 1,208 | 26,582 (0%) | 0% | 111.6 | 134,825 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 3,434 | 87,195 (0%) | 0% | 111.6 | 383,269 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 11,225 | 90,629 (0%) | 0% | 111.6 | 1,252,822 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.61 per share. | 14 Nov 2023 | 3,420 | 21,039 (0%) | 0% | 111.6 | 381,706 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 9,101 | 24,459 (0%) | 0% | 111.6 | 1,015,763 | Common Stock |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 111.61 per share. | 14 Nov 2023 | 1,396 | 12,147 (0%) | 0% | 111.6 | 155,808 | Common Stock |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2023 | 6,261 | 6,261 | - | - | Employee Stock Option (Right to Buy) | |
| Philip Binns | Senior Vice President | Grant, award, or other acquisition of securities at price $ 113.10 per share. | 11 Sep 2023 | 2,203 | 10,751 (0%) | 0% | 113.1 | 249,159 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 118.78 per share. | 23 Aug 2023 | 3,500 | 24,218 (0%) | 0% | 118.8 | 415,716 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.00 per share. | 27 Jul 2023 | 944 | 260,868 (0%) | 0% | 130 | 122,720 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jul 2023 | 944 | 65,218 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.12 per share. | 27 Jul 2023 | 944 | 261,812 (0%) | 0% | 42.1 | 39,761 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 128.87 per share. | 19 May 2023 | 171 | 15,358 (0%) | 0% | 128.9 | 22,037 | Common Stock |
| Henrik Ancher-Jensen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 134.77 per share. | 03 May 2023 | 132 | 70,805 (0%) | 0% | 134.8 | 17,790 | Common Stock |
| Henrik Ancher-Jensen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 134.77 per share. | 03 May 2023 | 132 | 70,982 (0%) | 0% | 134.8 | 17,790 | Common Stock |
| Dow R. Wilson | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 14,349 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 20,184 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 741 | 5,585 (0%) | 0% | 136.8 | 101,384 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 4,844 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 32,749 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 405 | 33,154 (0%) | 0% | 136.8 | 55,412 | Common Stock |
| Koh Boon Hwee | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 59,429 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 741 | 22,379 (0%) | 0% | 136.8 | 101,384 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 21,638 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Heidi Kunz | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 56,221 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Mikael Dolsten | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 4,018 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Susan H. Rataj | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 24,933 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Mala Anand | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 11,050 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Koh Boon Hwee | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 136.82 per share. | 16 Mar 2023 | 498 | 58,931 (0%) | 0% | 136.8 | 68,136 | Common Stock |
| Koh Boon Hwee | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 16 Mar 2023 | 1,658 | 59,429 (0%) | 0% | 136.8 | 226,848 | Common Stock |
| Dominique Grau | Senior Vice President | Gift of securities by or to the insider at price $ 159.06 per share. | 23 Jan 2023 | 52,286 | 52,286 (0%) | 0% | 159.1 | 8,316,745 | Common Stock |
| Dominique Grau | Senior Vice President | Gift of securities by or to the insider at price $ 159.06 per share. | 23 Jan 2023 | 52,286 | 40,091 (0%) | 0% | 159.1 | 8,316,745 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Sale of securities on an exchange or to another person at price $ 155.78 per share. | 14 Dec 2022 | 29,500 | 70,793 (0%) | 0% | 155.8 | 4,595,510 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 159.20 per share. | 13 Dec 2022 | 4,000 | 92,378 (0%) | 0% | 159.2 | 636,800 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 160.00 per share. | 13 Dec 2022 | 672 | 15,529 (0%) | 0% | 160 | 107,520 | Common Stock |
| Koh Boon Hwee | Director | Sale of securities on an exchange or to another person at price $ 152.21 per share. | 06 Dec 2022 | 13,000 | 57,752 (0%) | 0% | 152.2 | 1,978,692 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 155.65 per share. | 30 Nov 2022 | 3,235 | 84,464 (0%) | 0% | 155.7 | 503,528 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 154.63 per share. | 30 Nov 2022 | 9,700 | 87,699 (0%) | 0% | 154.6 | 1,499,912 | Common Stock |
| Heidi Kunz | Director | Sale of securities on an exchange or to another person at price $ 155.84 per share. | 23 Nov 2022 | 3,635 | 54,484 (0%) | 0% | 155.8 | 566,482 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 155.35 per share. | 23 Nov 2022 | 924 | 27,522 (0%) | 0% | 155.3 | 143,543 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 155.35 per share. | 23 Nov 2022 | 924 | 0 (0%) | 0% | 155.3 | 143,543 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 155.35 per share. | 23 Nov 2022 | 924 | 924 (0%) | 0% | 155.3 | 143,543 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 156.20 per share. | 23 Nov 2022 | 4,634 | 28,446 (0%) | 0% | 156.2 | 723,831 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 155.73 per share. | 22 Nov 2022 | 128,726 | 260,691 (0%) | 0% | 155.7 | 20,046,500 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 22 Nov 2022 | 128,726 | 389,417 (0%) | 0% | 40.8 | 5,252,021 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Nov 2022 | 128,726 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 153.90 per share. | 22 Nov 2022 | 7,545 | 46,499 (0%) | 0% | 153.9 | 1,161,176 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 153.21 per share. | 22 Nov 2022 | 2,746 | 16,201 (0%) | 0% | 153.2 | 420,715 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 7,492 | 260,691 (0%) | 0% | 146.2 | 1,095,255 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 995 | 100,293 (0%) | 0% | 146.2 | 145,459 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 1,050 | 54,044 (0%) | 0% | 146.2 | 153,500 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 1,750 | 116,057 (0%) | 0% | 146.2 | 255,833 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 1,067 | 96,378 (0%) | 0% | 146.2 | 155,985 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 1,418 | 97,399 (0%) | 0% | 146.2 | 207,297 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 367 | 33,080 (0%) | 0% | 146.2 | 53,652 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 1,120 | 79,096 (0%) | 0% | 146.2 | 163,733 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.19 per share. | 18 Nov 2022 | 249 | 18,947 (0%) | 0% | 146.2 | 36,401 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 2,713 | 268,183 (0%) | 0% | 144.4 | 391,866 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 386 | 101,288 (0%) | 0% | 144.4 | 55,754 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 395 | 55,094 (0%) | 0% | 144.4 | 57,054 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 679 | 117,807 (0%) | 0% | 144.4 | 98,075 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 519 | 97,445 (0%) | 0% | 144.4 | 74,964 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 537 | 98,817 (0%) | 0% | 144.4 | 77,564 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 142 | 33,447 (0%) | 0% | 144.4 | 20,510 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 457 | 80,216 (0%) | 0% | 144.4 | 66,009 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 144.44 per share. | 17 Nov 2022 | 353 | 19,196 (0%) | 0% | 144.4 | 50,987 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 2,013 | 270,896 (0%) | 0% | 147.1 | 296,153 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 148.19 per share. | 16 Nov 2022 | 6,775 | 270,896 (0%) | 0% | 148.2 | 1,003,987 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 16 Nov 2022 | 6,775 | 277,671 (0%) | 0% | 40.8 | 276,420 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2022 | 6,775 | 128,726 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 375 | 101,674 (0%) | 0% | 147.1 | 55,170 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 286 | 55,489 (0%) | 0% | 147.1 | 42,076 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 504 | 118,486 (0%) | 0% | 147.1 | 74,148 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 349 | 97,964 (0%) | 0% | 147.1 | 51,345 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 403 | 99,354 (0%) | 0% | 147.1 | 59,289 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 110 | 33,589 (0%) | 0% | 147.1 | 16,183 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 344 | 80,673 (0%) | 0% | 147.1 | 50,609 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.12 per share. | 16 Nov 2022 | 276 | 19,549 (0%) | 0% | 147.1 | 40,605 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 59,165 | 59,165 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 137,544 | 341,104 (0%) | 0% | 148 | 20,356,512 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 68,195 | 272,909 (0%) | 0% | 148 | 10,092,860 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 20,245 | 203,560 (0%) | 0% | 148 | 2,996,260 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 19,280 | 110,443 (0%) | 0% | 148 | 2,853,440 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 10,093 | 10,093 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 3,453 | 91,163 (0%) | 0% | 148 | 511,044 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 8,394 | 102,049 (0%) | 0% | 148 | 1,242,312 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 8,891 | 55,775 (0%) | 0% | 148 | 1,315,868 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 8,469 | 8,469 | - | - | Employee Stock Option (Right to Buy) | |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 19,280 | 64,666 (0%) | 0% | 148 | 2,853,440 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 2,898 | 45,386 (0%) | 0% | 148 | 428,904 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 32,134 | 130,370 (0%) | 0% | 148 | 4,755,832 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 15,661 | 15,661 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 11,380 | 118,990 (0%) | 0% | 148 | 1,684,240 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 5,359 | 98,236 (0%) | 0% | 148 | 793,132 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 19,603 | 107,372 (0%) | 0% | 148 | 2,901,244 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 9,059 | 98,313 (0%) | 0% | 148 | 1,340,732 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 8,701 | 8,701 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 2,977 | 87,769 (0%) | 0% | 148 | 440,596 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 26,029 | 112,195 (0%) | 0% | 148 | 3,852,292 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 4,287 | 86,166 (0%) | 0% | 148 | 634,476 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 12,438 | 99,757 (0%) | 0% | 148 | 1,840,824 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 12,529 | 12,529 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 6,748 | 36,155 (0%) | 0% | 148 | 998,704 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 1,135 | 29,407 (0%) | 0% | 148 | 167,980 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 2,456 | 33,699 (0%) | 0% | 148 | 363,488 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 3,318 | 3,318 | - | - | Employee Stock Option (Right to Buy) | |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 7,646 | 81,017 (0%) | 0% | 148 | 1,131,608 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 10,093 | 10,093 | - | - | Employee Stock Option (Right to Buy) | |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 3,453 | 68,097 (0%) | 0% | 148 | 511,044 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 20,566 | 88,663 (0%) | 0% | 148 | 3,043,768 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 3,176 | 13,907 (0%) | 0% | 148 | 470,048 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Nov 2022 | 9,281 | 9,281 | - | - | Employee Stock Option (Right to Buy) | |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.00 per share. | 15 Nov 2022 | 3,632 | 19,825 (0%) | 0% | 148 | 537,536 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 148.00 per share. | 15 Nov 2022 | 9,550 | 23,457 (0%) | 0% | 148 | 1,413,400 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 8,043 | 183,315 (0%) | 0% | 148.3 | 1,192,857 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 735 | 87,710 (0%) | 0% | 148.3 | 109,008 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 794 | 42,488 (0%) | 0% | 148.3 | 117,758 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 1,860 | 92,877 (0%) | 0% | 148.3 | 275,857 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 794 | 84,792 (0%) | 0% | 148.3 | 117,758 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 1,091 | 81,879 (0%) | 0% | 148.3 | 161,806 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 284 | 28,272 (0%) | 0% | 148.3 | 42,120 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 737 | 64,644 (0%) | 0% | 148.3 | 109,304 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.31 per share. | 11 Nov 2022 | 127 | 10,731 (0%) | 0% | 148.3 | 18,835 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 138.31 per share. | 09 Nov 2022 | 6,775 | 191,358 (0%) | 0% | 138.3 | 937,050 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2022 | 6,775 | 135,501 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 09 Nov 2022 | 6,775 | 198,133 (0%) | 0% | 40.8 | 276,420 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 02 Nov 2022 | 6,775 | 198,133 (0%) | 0% | 40.8 | 276,420 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Nov 2022 | 6,775 | 142,276 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 140.61 per share. | 02 Nov 2022 | 6,775 | 191,358 (0%) | 0% | 140.6 | 952,633 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 139.50 per share. | 01 Nov 2022 | 3,600 | 43,280 (0%) | 0% | 139.5 | 502,200 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 134.43 per share. | 26 Oct 2022 | 6,775 | 191,358 (0%) | 0% | 134.4 | 910,763 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Oct 2022 | 6,775 | 149,051 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 26 Oct 2022 | 6,775 | 198,133 (0%) | 0% | 40.8 | 276,420 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Oct 2022 | 6,775 | 155,826 | - | - | Employee Stock Option (Right to Buy) | |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.11 per share. | 19 Oct 2022 | 6,775 | 191,358 (0%) | 0% | 130.1 | 881,495 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 19 Oct 2022 | 6,775 | 198,133 (0%) | 0% | 40.8 | 276,420 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 122.89 per share. | 28 Sep 2022 | 2,103 | 13,217 (0%) | 0% | 122.9 | 258,438 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 133.25 per share. | 14 Sep 2022 | 865 | 28,464 (0%) | 0% | 133.2 | 115,261 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 137.45 per share. | 09 Sep 2022 | 5,839 | 82,933 (0%) | 0% | 137.5 | 802,571 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 134.33 per share. | 08 Sep 2022 | 2,506 | 15,320 (0%) | 0% | 134.3 | 336,641 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 134.56 per share. | 03 Aug 2022 | 2,303 | 94,721 (0%) | 0% | 134.6 | 309,892 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 118.62 per share. | 30 Jun 2022 | 1,000 | 17,826 (0%) | 0% | 118.6 | 118,625 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 127.43 per share. | 02 Jun 2022 | 5,879 | 88,736 (0%) | 0% | 127.4 | 749,179 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 122.40 per share. | 19 May 2022 | 171 | 18,826 (0%) | 0% | 122.4 | 20,930 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 119.38 per share. | 13 May 2022 | 183 | 94,615 (0%) | 0% | 119.4 | 21,847 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 119.38 per share. | 13 May 2022 | 226 | 65,251 (0%) | 0% | 119.4 | 26,980 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2022 | 5,598 | 5,598 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 122.40 per share. | 03 May 2022 | 1,645 | 88,125 (0%) | 0% | 122.4 | 201,348 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 136.21 per share. | 18 Mar 2022 | 1,210 | 46,828 (0%) | 0% | 136.2 | 164,814 | Common Stock |
| Dow R. Wilson | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 12,610 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 18,419 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 797 | 3,165 (0%) | 0% | 136.8 | 109,046 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 2,368 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 30,457 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 435 | 30,892 (0%) | 0% | 136.8 | 59,517 | Common Stock |
| Koh Boon Hwee | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 71,223 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Koh Boon Hwee | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 136.82 per share. | 17 Mar 2022 | 536 | 70,687 (0%) | 0% | 136.8 | 73,336 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 797 | 19,852 (0%) | 0% | 136.8 | 109,046 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 19,055 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Heidi Kunz | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 57,849 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Mikael Dolsten | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 2,352 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Susan H. Rataj | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 23,275 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Mala Anand | Director | Grant, award, or other acquisition of securities at price $ 136.82 per share. | 17 Mar 2022 | 1,785 | 9,392 (0%) | 0% | 136.8 | 244,224 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 161.00 per share. | 29 Dec 2021 | 3,669 | 85,404 (0%) | 0% | 161 | 590,709 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 148.82 per share. | 20 Dec 2021 | 123,459 | 191,187 (0%) | 0% | 148.8 | 18,373,168 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 151.89 per share. | 02 Dec 2021 | 800 | 0 (0%) | 0% | 151.9 | 121,512 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 150.90 per share. | 30 Nov 2021 | 800 | 32,725 (0%) | 0% | 150.9 | 120,720 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 152.04 per share. | 30 Nov 2021 | 699 | 33,525 (0%) | 0% | 152.0 | 106,274 | Common Stock |
| Michael R. McMullen | CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 7,493 | 314,646 (0%) | 0% | 164.3 | 1,231,100 | Common Stock |
| Henrik Ancher-Jensen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 996 | 86,332 (0%) | 0% | 164.3 | 163,643 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 1,051 | 48,022 (0%) | 0% | 164.3 | 172,679 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 1,751 | 96,977 (0%) | 0% | 164.3 | 287,689 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 1,068 | 89,073 (0%) | 0% | 164.3 | 175,472 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 1,418 | 94,728 (0%) | 0% | 164.3 | 232,977 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 368 | 44,021 (0%) | 0% | 164.3 | 60,462 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 1,121 | 62,544 (0%) | 0% | 164.3 | 184,180 | Common Stock |
| Padraig McDonnell | Senior Vice President | Sale of securities on an exchange or to another person at price $ 165.00 per share. | 19 Nov 2021 | 1,500 | 18,997 (0%) | 0% | 165 | 247,500 | Common Stock |
| Padraig McDonnell | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 164.30 per share. | 19 Nov 2021 | 251 | 20,497 (0%) | 0% | 164.3 | 41,239 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 162.16 per share. | 18 Nov 2021 | 404 | 404 (0%) | 0% | 162.2 | 65,513 | Common Stock |
| Otis W. Brawley | Director | Grant, award, or other acquisition of securities at price $ 162.16 per share. | 18 Nov 2021 | 179 | 583 (0%) | 0% | 162.2 | 29,027 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 2,713 | 322,139 (0%) | 0% | 161.5 | 438,258 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 386 | 87,328 (0%) | 0% | 161.5 | 62,354 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 395 | 49,073 (0%) | 0% | 161.5 | 63,808 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 678 | 98,728 (0%) | 0% | 161.5 | 109,524 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 518 | 90,141 (0%) | 0% | 161.5 | 83,678 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 536 | 96,146 (0%) | 0% | 161.5 | 86,585 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 142 | 44,389 (0%) | 0% | 161.5 | 22,939 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 457 | 63,665 (0%) | 0% | 161.5 | 73,824 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.54 per share. | 17 Nov 2021 | 353 | 20,748 (0%) | 0% | 161.5 | 57,024 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 136,087 | 400,349 (0%) | 0% | 161.4 | 21,963,081 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 16,240 | 264,262 (0%) | 0% | 161.4 | 2,620,974 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 75,497 | 324,852 (0%) | 0% | 161.4 | 12,184,461 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 62,451 | 62,451 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 19,242 | 97,626 (0%) | 0% | 161.4 | 3,105,466 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 3,181 | 78,384 (0%) | 0% | 161.4 | 513,382 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 9,628 | 9,628 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 9,912 | 87,714 (0%) | 0% | 161.4 | 1,599,698 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 19,242 | 59,742 (0%) | 0% | 161.4 | 3,105,466 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 8,847 | 8,847 | - | - | Employee Stock Option (Right to Buy) | |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 2,301 | 40,500 (0%) | 0% | 161.4 | 371,358 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 10,274 | 49,468 (0%) | 0% | 161.4 | 1,658,121 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 15,613 | 15,613 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 11,196 | 99,406 (0%) | 0% | 161.4 | 1,806,922 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 31,615 | 110,602 (0%) | 0% | 161.4 | 5,102,345 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 4,060 | 78,987 (0%) | 0% | 161.4 | 655,243 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 8,847 | 8,847 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 2,809 | 82,278 (0%) | 0% | 161.4 | 453,345 | Common Stock |
| Dominique Grau | Senior Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 19,242 | 101,520 (0%) | 0% | 161.4 | 3,105,466 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 10,861 | 90,659 (0%) | 0% | 161.4 | 1,752,857 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 14,579 | 96,682 (0%) | 0% | 161.4 | 2,352,905 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 3,248 | 84,801 (0%) | 0% | 161.4 | 524,195 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 26,460 | 111,261 (0%) | 0% | 161.4 | 4,270,379 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 12,490 | 12,490 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 3,383 | 3,383 | - | - | Employee Stock Option (Right to Buy) | |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 880 | 40,855 (0%) | 0% | 161.4 | 142,023 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 6,872 | 47,727 (0%) | 0% | 161.4 | 1,109,072 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 3,196 | 44,531 (0%) | 0% | 161.4 | 515,802 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 2,774 | 54,949 (0%) | 0% | 161.4 | 447,696 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 10,669 | 10,669 | - | - | Employee Stock Option (Right to Buy) | |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 6,648 | 66,170 (0%) | 0% | 161.4 | 1,072,921 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 17,869 | 72,818 (0%) | 0% | 161.4 | 2,883,878 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 3,297 | 22,303 (0%) | 0% | 161.4 | 532,103 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2021 | 8,977 | 8,977 | - | - | Employee Stock Option (Right to Buy) | |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 161.39 per share. | 16 Nov 2021 | 1,202 | 21,101 (0%) | 0% | 161.4 | 193,991 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Grant, award, or other acquisition of securities at price $ 161.39 per share. | 16 Nov 2021 | 2,335 | 19,006 (0%) | 0% | 161.4 | 376,846 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 5,260 | 248,022 (0%) | 0% | 160.9 | 846,229 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 8,043 | 253,282 (0%) | 0% | 160.9 | 1,293,958 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 799 | 75,203 (0%) | 0% | 160.9 | 128,543 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 1,079 | 76,002 (0%) | 0% | 160.9 | 173,590 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 616 | 38,199 (0%) | 0% | 160.9 | 99,102 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 794 | 38,815 (0%) | 0% | 160.9 | 127,739 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 1,869 | 74,927 (0%) | 0% | 160.9 | 300,685 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 1,138 | 80,402 (0%) | 0% | 160.9 | 183,081 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 933 | 79,469 (0%) | 0% | 160.9 | 150,101 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 1,091 | 82,392 (0%) | 0% | 160.9 | 175,520 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 839 | 81,553 (0%) | 0% | 160.9 | 134,978 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 737 | 52,175 (0%) | 0% | 160.9 | 118,569 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 127 | 16,789 (0%) | 0% | 160.9 | 20,432 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 12 Nov 2021 | 118 | 16,671 (0%) | 0% | 160.9 | 18,984 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 117.37 per share. | 31 Oct 2021 | 400 | 40 (0%) | 0% | 117.4 | 46,948 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | 31 Oct 2021 | 1,000 | 0 (0%) | 0% | 172.0 | 171,980 | Common Stock | |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 138.13 per share. | 31 Oct 2021 | 1,000 | 40 (0%) | 0% | 138.1 | 138,130 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 123.50 per share. | 31 Oct 2021 | 1,000 | 40 (0%) | 0% | 123.5 | 123,500 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | 31 Oct 2021 | 3,727 | 30,682 (0%) | 0% | 118.0 | 439,657 | Common Stock | |
| Mikael Dolsten | Director | Grant, award, or other acquisition of securities at price $ 172.44 per share. | 22 Sep 2021 | 567 | 567 (0%) | 0% | 172.4 | 97,773 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Gift of securities by or to the insider at price $ 173.30 per share. | 25 Aug 2021 | 1,000 | 40,368 (0%) | 0% | 173.3 | 173,300 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 25 Aug 2021 | 284 | 40,204 (0%) | 0% | 160.9 | 45,690 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 160.88 per share. | 25 Aug 2021 | 229 | 39,975 (0%) | 0% | 160.9 | 36,842 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2021 | 9,033 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 165.06 per share. | 18 Aug 2021 | 9,033 | 81,419 (0%) | 0% | 165.1 | 1,490,942 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 18 Aug 2021 | 9,033 | 90,452 (0%) | 0% | 40.8 | 368,546 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 155.00 per share. | 05 Aug 2021 | 9,033 | 81,419 (0%) | 0% | 155 | 1,400,115 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 05 Aug 2021 | 9,033 | 90,452 (0%) | 0% | 40.8 | 368,546 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Aug 2021 | 9,033 | 9,033 | - | - | Employee Stock Option (Right to Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 153.86 per share. | 03 Aug 2021 | 2,327 | 76,796 (0%) | 0% | 153.9 | 358,032 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jun 2021 | 1,968 | 18,066 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 145.10 per share. | 17 Jun 2021 | 1,968 | 81,419 (0%) | 0% | 145.1 | 285,563 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 17 Jun 2021 | 1,968 | 83,387 (0%) | 0% | 40.8 | 80,294 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 145.03 per share. | 15 Jun 2021 | 3,578 | 81,419 (0%) | 0% | 145.0 | 518,917 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 15 Jun 2021 | 3,578 | 84,997 (0%) | 0% | 40.8 | 145,982 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 15 Jun 2021 | 3,487 | 84,906 (0%) | 0% | 40.8 | 142,270 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 145.01 per share. | 15 Jun 2021 | 3,487 | 81,419 (0%) | 0% | 145.0 | 505,653 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2021 | 3,578 | 23,521 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2021 | 3,487 | 20,034 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2021 | 24,841 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 14 Jun 2021 | 24,841 | 120,633 (0%) | 0% | 40.8 | 1,013,513 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Sale of securities on an exchange or to another person at price $ 143.66 per share. | 14 Jun 2021 | 43,731 | 76,902 (0%) | 0% | 143.7 | 6,282,527 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 142.90 per share. | 10 Jun 2021 | 16,289 | 83,423 (0%) | 0% | 142.9 | 2,327,698 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 138.42 per share. | 28 May 2021 | 1,000 | 16,916 (0%) | 0% | 138.4 | 138,420 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 136.16 per share. | 27 May 2021 | 13,465 | 39,579 (0%) | 0% | 136.2 | 1,833,351 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 130.21 per share. | 19 May 2021 | 164 | 17,916 (0%) | 0% | 130.2 | 21,354 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 131.15 per share. | 14 May 2021 | 183 | 99,712 (0%) | 0% | 131.1 | 24,000 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 131.15 per share. | 14 May 2021 | 1,268 | 52,786 (0%) | 0% | 131.1 | 166,298 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 137.00 per share. | 23 Apr 2021 | 500 | 53,029 (0%) | 0% | 137 | 68,500 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 135.00 per share. | 22 Apr 2021 | 9,053 | 261,105 (0%) | 0% | 135 | 1,222,155 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 132.50 per share. | 13 Apr 2021 | 8,966 | 270,158 (0%) | 0% | 132.5 | 1,187,995 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.26 per share. | 08 Apr 2021 | 15,095 | 279,124 (0%) | 0% | 130.3 | 1,966,275 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Sale of securities on an exchange or to another person at price $ 127.50 per share. | 31 Mar 2021 | 1,000 | 53,936 (0%) | 0% | 127.5 | 127,500 | Common Stock |
| Dow R. Wilson | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 10,766 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 986 | 16,543 (0%) | 0% | 121.6 | 119,891 | Common Stock |
| George A. Scangos | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 15,557 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Paul N. Clark | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 95,234 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 28,063 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Daniel Podolsky | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 452 | 28,515 (0%) | 0% | 121.6 | 54,960 | Common Stock |
| Koh Boon Hwee | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 69,921 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Koh Boon Hwee | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 121.59 per share. | 18 Mar 2021 | 555 | 69,366 (0%) | 0% | 121.6 | 67,484 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 16,353 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Hans Edgar Bishop | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 822 | 17,175 (0%) | 0% | 121.6 | 99,949 | Common Stock |
| Heidi Kunz | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 55,767 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Susan H. Rataj | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 21,490 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Mala Anand | Director | Grant, award, or other acquisition of securities at price $ 121.59 per share. | 18 Mar 2021 | 1,850 | 7,607 (0%) | 0% | 121.6 | 224,947 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Sale of securities on an exchange or to another person at price $ 124.17 per share. | 22 Feb 2021 | 5,000 | 41,229 (0%) | 0% | 124.2 | 620,850 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 130.00 per share. | 16 Feb 2021 | 20,766 | 294,219 (0%) | 0% | 130 | 2,699,580 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 133.00 per share. | 16 Feb 2021 | 500 | 53,529 (0%) | 0% | 133 | 66,500 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 129.31 per share. | 16 Feb 2021 | 500 | 54,029 (0%) | 0% | 129.3 | 64,655 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 135.11 per share. | 16 Feb 2021 | 13,745 | 81,325 (0%) | 0% | 135.1 | 1,857,087 | Common Stock |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2021 | 9,034 | 27,099 | - | - | Employee Stock Option (Right to Buy) | |
| Dominique Grau | Senior Vice President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.80 per share. | 16 Feb 2021 | 9,034 | 95,070 (0%) | 0% | 40.8 | 368,587 | Common Stock |
| Dominique Grau | Senior Vice President | Sale of securities on an exchange or to another person at price $ 130.14 per share. | 16 Feb 2021 | 6,041 | 86,036 (0%) | 0% | 130.1 | 786,194 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 123.74 per share. | 01 Feb 2021 | 41,978 | 314,985 (0%) | 0% | 123.7 | 5,194,232 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 120.26 per share. | 01 Feb 2021 | 21,212 | 356,963 (0%) | 0% | 120.3 | 2,550,955 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 127.35 per share. | 19 Jan 2021 | 367 | 54,513 (0%) | 0% | 127.3 | 46,737 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Sale of securities on an exchange or to another person at price $ 127.27 per share. | 14 Jan 2021 | 500 | 54,880 (0%) | 0% | 127.3 | 63,635 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 115.63 per share. | 01 Dec 2020 | 85,842 | 415,347 (0%) | 0% | 115.6 | 9,925,910 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 115.33 per share. | 01 Dec 2020 | 18 | 46,183 (0%) | 0% | 115.3 | 2,076 | Common Stock |
| Koh Boon Hwee | Director | Sale of securities on an exchange or to another person at price $ 114.51 per share. | 30 Nov 2020 | 20,000 | 68,050 (0%) | 0% | 114.5 | 2,290,200 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 82,635 | 464,017 (0%) | 0% | 108.7 | 8,980,772 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 1,212 | 95,494 (0%) | 0% | 108.7 | 131,720 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 9,639 | 55,380 (0%) | 0% | 108.7 | 1,047,567 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 1,751 | 79,123 (0%) | 0% | 108.7 | 190,299 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 13,413 | 92,077 (0%) | 0% | 108.7 | 1,457,725 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 15,374 | 99,830 (0%) | 0% | 108.7 | 1,670,846 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 493 | 46,201 (0%) | 0% | 108.7 | 53,579 | Common Stock |
| Samraat S. Raha | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 11,342 | 54,923 (0%) | 0% | 108.7 | 1,232,649 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 108.68 per share. | 19 Nov 2020 | 1,590 | 18,080 (0%) | 0% | 108.7 | 172,801 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 8,104 | 546,652 (0%) | 0% | 106.0 | 858,619 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 509 | 96,792 (0%) | 0% | 106.0 | 53,929 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 303 | 65,103 (0%) | 0% | 106.0 | 32,103 | Common Stock |
| Dominique Grau | Senior Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 1,351 | 105,490 (0%) | 0% | 105.9 | 143,138 | Common Stock |
| Jacob Thaysen | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 1,081 | 115,204 (0%) | 0% | 106.0 | 114,532 | Common Stock |
| Rodney Gonsalves | V.P., Corporate Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.96 per share. | 18 Nov 2020 | 466 | 46,694 (0%) | 0% | 106.0 | 49,377 | Common Stock |
| Padraig McDonnell | Sr. Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 105.95 per share. | 18 Nov 2020 | 225 | 19,670 (0%) | 0% | 106.0 | 23,839 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 108,359 | 608,481 (0%) | 0% | 109.9 | 11,904,320 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2020 | 91,590 | 91,590 | - | - | Employee Stock Option (Right-to-Buy) | |
| Michael R. McMullen | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 109.86 per share. | 17 Nov 2020 | 53,725 | 554,756 (0%) | 0% | 109.9 | 5,902,229 | Common Stock |
| Michael R. McMullen | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 21,882 | 500,122 (0%) | 0% | 109.9 | 2,403,957 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2020 | 13,739 | 13,739 | - | - | Employee Stock Option (Right-to-Buy) | |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 3,282 | 89,728 (0%) | 0% | 109.9 | 360,561 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 13,705 | 103,433 (0%) | 0% | 109.9 | 1,505,631 | Common Stock |
| Henrik Ancher-Jensen | Sr Vice President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 109.86 per share. | 17 Nov 2020 | 6,218 | 97,215 (0%) | 0% | 109.9 | 683,109 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2020 | 13,322 | 13,322 | - | - | Employee Stock Option (Right-to-Buy) | |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 3,183 | 57,907 (0%) | 0% | 109.9 | 349,684 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 14,358 | 72,265 (0%) | 0% | 109.9 | 1,577,370 | Common Stock |
| Michael Tang | SVP, General Counsel, and Sec. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 109.86 per share. | 17 Nov 2020 | 6,943 | 65,322 (0%) | 0% | 109.9 | 762,758 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 5,470 | 53,399 (0%) | 0% | 109.9 | 600,934 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2020 | 22,898 | 22,898 | - | - | Employee Stock Option (Right-to-Buy) | |
| Robert W. McMahon | Sr. VP and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 109.86 per share. | 17 Nov 2020 | 27,019 | 80,874 (0%) | 0% | 109.9 | 2,968,307 | Common Stock |
| Robert W. McMahon | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 109.86 per share. | 17 Nov 2020 | 54,494 | 107,893 (0%) | 0% | 109.9 | 5,986,711 | Common Stock |